October 31, 2006
Journal Club by Natalina Quarto, Ph.D.
Rodda SJ, McMahon AP. Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors. Development 2006; 133(16):3231-44.
 Download Article (103106.pdf)

November 14, 2006
Journal Club by Yue Xu, M.D., Ph.D.
Kortesidis A, Zannettino A, Isenmann S, et al. Stromal-derived factor-1 promotes the growth, survival, and development of human bone marrow stromal stem cells. Blood 2005; 105(10):3793-801.
 Download Article (111406.pdf)

November 28, 2006
Journal Club by Wuyi Kong, M.D., Ph.D.
Ozdamar B, Bose R, Barrios-Rodiles M, et al. Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity. Science 2005; 307(5715):1603-9.
 Download Article (112806.pdf)

December 11, 2006
Journal Club by Bethany Slater, M.D.
Gross, J. B. and J. Hanken (2005). "Cranial neural crest contributes to the bony skull vault in adult Xenopus laevis: insights from cell labeling studies." J Exp Zoolog B Mol Dev Evol 304(2): 169-76.
 Download Article (121106.pdf)

January 9, 2007
Journal Club by Paris Butler, M.D.
Oyadomari, S., A. Koizumi, et al. (2002). "Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes." J Clin Invest 109(4): 525-32.
 Download Article (010907.pdf)

January 23, 2007
Journal Club by Shuli Li, M.D., Ph.D.
Chen, Y. et al. Beta-catenin signaling pathway is crucial for bone morphogenetic protein 2 to induce new bone formation. J Biol Chem 282, 526-33 (2007).
 Download Article (012307.pdf)

February 6, 2007
Journal Club by Unsal Kuscuogly, Ph.D.
Paik, J.H. et al. FoxOs Are Lineage-Restricted Redundant Tumor Suppressors and Regulate Endothelial Cell Homeostasis. Cell 128, 309-23 (2007).
Tothova, Z. et al. FoxOs Are Critical Mediators of Hematopoietic Stem Cell Resistance to Physiologic Oxidative Stress. Cell 128, 325-339 (2007).
 Download Article (020607.pdf)

February 20, 2007
Journal Club by Kelly Lenton, Ph.D.
Niedermaier, M. et al. An inversion involving the mouse Shh locus results in brachydactyly through dysregulation of Shh expression. The journal of clinical investigation 115, 900-909 (2005).
 Download Article (022007.pdf)

March 6, 2007
Journal Club by Christine Ham, M.D.
Tsuji, K. et al. BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing. Nat Genet 38, 1424-1429 (2006).
 Download Article (030607.pdf)

March 20, 2007
Journal Club by Min Hu, M.D., Ph.D.
Xue, W. et al. Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature 445, 656-660 (2007).
 Download Article (032007.pdf)

April 3, 2007
Journal Club by Cindy Luppen, Ph.D.
Katayama, Y. et al. Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow. Cell 124, 407-21 (2006).
 Download Article (040307.pdf)

April 17, 2007
Journal Club by Nathan Morrell
Mikels, A.J. & Nusse, R. Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context. PLoS Biol 4, e115 (2006).
 Download Article (041707.pdf)

May 1, 2007
Journal Club by Zhen Wang, M.D.
Engler, A.J., Sen, S., Sweeney, H.L. & Discher, D.E. Matrix elasticity directs stem cell lineage specification. Cell 126, 677-89 (2006).
 Download Article (050107.pdf)

May 15, 2007
Journal Club by Deepak Gupta, MD
Scherner, O., Meurer, S.K., Tihaa, L., Gressner, A.M. & Weiskirchen, R. Endoglin Differentially Modulates Antagonistic Transforming Growth Factor-beta1 and BMP-7 Signaling. J Biol Chem 282, 13934-43 (2007).
 Download Article (051507.pdf)

May 22, 2007
Journal Club by Matthew Kwan, MD
Yoon, B.S. et al. BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development 133, 4667-78 (2006).
 Download Article (052207.pdf)